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Anticoagulants: Phenobarbital lowers the plasma levels of dicumarol (name Earlier made use of: bishydroxycoumarin) and will cause a decrease in anticoagulant activity as measured via the prothrombin time. Barbiturates can induce hepatic microsomal enzymes causing increased metabolism and lessened anticoagulant reaction of oral anticoagulants (e. (See "Drug Abuse and Dependence" http://rivertgqyf.designi1.com/10973531/nembutal-vs-valium-no-further-a-mystery

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